Personal Computer Stormwater Management Model (PCSWMM) was applied to investigate: (1) hydrological responses in the Myponga catchment as a result of land use changes; and (2) the possibility of adopting Water Sensitive Urban Design (WSUD) technologies (bio-retention cells) to manage resulting floods. Calibrated and validated models predicted the measured data with satisfactory accuracy and reliability. Different urbanization scenarios were tested. When the level of urbanization increased from 10% to 70%, mean discharge increased from 45% to 322%. Frequency of flood at 2-year Average Recurrence Interval (ARI) increased from 1 to 44 and frequency of floods at 100-year ARI increased from none to 8. At 70% urbanisation, trialled bio-retention facilities used as WSUD measures almost completely ameliorated 2-year ARI floods by reducing the frequency of such events from 44 to 2. Floods at smaller ARIs (2, 5, 10 and 20 years) were effectively managed by WSUD measures while floods at 50- and 100-year ARIs remained unchanged. The overall results improve understanding of the severity of the impacts of land use changes on the hydrology of a catchment and the ability of bio-retention cells to alleviate the risk of small to medium floods in the Myponga catchment.